PhrmaSec Limited is a Hong Kong University-based biotech spin-off company, rooted in the research done at Professor Billy KC Chow’s lab. Research led by Professor Chow and other groups has demonstrated that Secretin knockout animals will develop hypertension and related disorders as Secretin is of vital importance in water/salt homeostasis. Therefore, at PhrmaSec, by using an innovative approach, state-of-the-art technology and high-throughput in vitro and in silico screening, we have identified five therapeutic molecules that can target Secretin Receptor to function as anti-hypertensive compounds. KSD171990 is being selected for pre-clinical studies after comparison is made.